📄 Category

psychiatry and clinical psychology

217 papers

Understanding the human mind and treating mental health conditions requires a deep blend of biological insight and behavioral science. This category explores the cutting-edge research shaping how we diagnose and treat psychiatric disorders, from depression and anxiety to complex neurological conditions. Here, you will find the latest discoveries that bridge the gap between clinical observation and molecular mechanisms, offering fresh perspectives on patient care and therapeutic innovation.

Gist.Science brings these vital studies directly to you by monitoring medRxiv, the leading preprint server for health sciences. As soon as new manuscripts appear in this field, our team processes them to provide both accessible plain-language summaries and detailed technical overviews. This ensures that complex findings are understandable for everyone, from curious readers to busy professionals who need quick, accurate insights without wading through dense academic prose.

Below are the most recent psychiatry and clinical psychology preprints, curated and summarized to keep you informed on the evolving landscape of mental health research.

📄 psychiatry and clinical psychology

Excess mortality after mental disorder diagnosis within and outside specialist psychiatric care: nationwide cohort study

This nationwide Finnish cohort study reveals that while mental disorder diagnoses are generally associated with increased mortality, excess death rates are often transient and normalize within two years for individuals with common non-psychotic disorders treated outside specialist care, whereas elevated risks persist for those with substance use disorders, psychotic conditions, or those receiving specialist psychiatric treatment.

Suokas, K., Gutvilig, M., Komulainen, K., Alho, J., McGrath, J. J., Pirkola, S., Lumme, S., Elovainio, M., Hakulinen, C.2026-11-11
📄 psychiatry and clinical psychology

Rapid antidepressant effects of psilocybin without increased SV2A binding: baseline binding predicts response

In a randomized controlled trial of patients with major depressive disorder, a single dose of psilocybin produced rapid and sustained antidepressant effects without a detectable group-level increase in synaptic density (measured by SV2A binding via [11C]UCB-J PET), though higher baseline synaptic density predicted a greater clinical response.

Yngwe, H., Plaven Sigray, P., Andersson, M., Bolin, M., Beckman, M., Ekman, C.-J., Tiger, M., Lundberg, J.2026-11-08
📄 psychiatry and clinical psychology

Co-production of an oral health intervention: Enabling Service Users with Severe Mental Illness to Learn about and Engage (SMILE) with Good Oral Health

This paper reports on the co-production process, guided by the Hawkins framework, which involved service users with severe mental illness and health professionals to develop an integrated oral health intervention for community mental health settings, consisting of five core components and supporting materials, prior to a planned feasibility study.

Mishu, M. P., Kika, N., Tkach, E., Bird, J., Cupac, J., Daniel, S., Horspool, M., Johnston, G., Killaspy, H., Marshman (…)2026-11-08
📄 psychiatry and clinical psychology

Understanding How the Self-Regulation in Sport Practice Survey is Received by Mental Performance Consultants for Prospective Use in Applied Practice

This study found that while most Canadian Mental Performance Consultants view the Self-Regulation in Sport Practice (SRSP) survey as a valuable tool for enhancing athlete self-awareness and case conceptualization, its prospective application is complicated by philosophical divisions and skepticism regarding quantitative assessment among some practitioners.

Young, B. W., Hoar, S., Bain, L., Baker, J.2026-10-31
📄 psychiatry and clinical psychology

Prevalence and Sociodemographic Correlates of Depression and Thoughts of Self-Harm Among Adolescents in Five Low- and Middle-Income Countries: Evidence from the Demographic and Health Survey Program

This study utilizes Demographic and Health Survey data from five low- and middle-income countries to reveal that while probable depression is relatively uncommon among adolescents, thoughts of death or self-harm affect approximately one in fourteen, with significantly higher prevalence among girls and substantial variation across national contexts.

Jäggi, L., Aryal, A., Muleya, C., Malimabe, M., Cambaco, O., Fink, G., Falgas-Bague, I.2026-10-31
📄 psychiatry and clinical psychology

Statistical analysis plan for the feasibility trial assessing external trigeminal nerve stimulation versus sham stimulation for ADHD in children and adolescents aged 7 to 17 years (the eTNS4ADHD trial)

This paper outlines the prespecified statistical analysis plan for the eTNS4ADHD feasibility trial, a multicentre randomised pilot study designed to evaluate the recruitment, compliance, and acceptability of active versus sham external trigeminal nerve stimulation in children and adolescents with ADHD to inform the design of a future definitive clinical trial.

Juul, S., Olsen, M. H., Nestved, S. K., Quistgaard, M., Edemann-Callesen, H., Lykke Huus, C.-M., Karstoft, C., Barisic (…)2026-10-30
📄 psychiatry and clinical psychology

Post-psychedelic and meditation-related challenges: a protocol for a mixed-methods longitudinal-observational study

This paper outlines a mixed-methods, longitudinal-observational study protocol designed to characterize the clinical features, longitudinal course, and functional impacts of persisting adverse effects following psychedelic use and meditation practice by comparing two parallel groups of 800 participants through surveys, ambulatory assessments, and qualitative interviews.

Lipson, J., Canby, N., Salako, Z., Kaplan, D., Arconada Alvarez, S. J., Levin-Aspenson, H., Britton, W., Rae, A., Korthu (…)2026-10-29
📄 psychiatry and clinical psychology

Synaptic density (SV2A) tracks illness chronicity rather than symptom severity in major depressive disorder

This study challenges previous findings by demonstrating that in unmedicated individuals with major depressive disorder, synaptic density (measured by SV2A binding) correlates with the chronicity of the current depressive episode rather than the severity of symptoms.

Yngwe, H., Plaven Sigray, P., Andersson, M., Bolin, M., Beckman, M., Ekman, C.-J., Tiger, M., Lundberg, J.2026-10-29